Brain work,neurons actually fire

 

MIKE MCRAE
22 DEC 2017

The human brain contains a little over 80-odd billion neurons, each joining with other cells to create trillions of connections called synapses.

The numbers are mind-boggling, but the way each individual nerve cell contributes to the brain’s functions is still an area of contention. A new study has overturned a hundred-year-old assumption on what exactly makes a neuron ‘fire’, posing new mechanisms behind certain neurological disorders.

French neuroscientist named Louis Lapicque proposed a model to describe how the voltage of a nerve cell’s membrane increases as a current is applied.

Once reaching a certain threshold, the neuron reacts with a spike of activity, after which the membrane’s voltage resets.

What this means is a neuron won’t send a message unless it collects a strong enough signal.

Lapique’s equations weren’t the last word on the matter, not by far. But the basic principle of his integrate-and-fire model has remained relatively unchallenged in subsequent descriptions, today forming the foundation of most neuronal computational schemes.

http://www.sciencealert.com

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